SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* Cardama Alfonso Quintas (Last) (First) (Middle) C/O TCR2 THERAPEUTICS 100 BINNEY STREET (Street) CAMBRIDGE MA 02142 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol TCR2 THERAPEUTICS INC. [ TCRR ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner X Officer (give title below) Other (specify below) Chief Medical Officer
	3. Date of Earliest Transaction (Month/Day/Year) 11/17/2022
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock								46,915	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	$16.11	11/17/2022		D			5,799	(1)	04/10/2029	Common Stock	5,799	$0.00(2)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		1,933		(4)	(4)	Common Stock	1,933	$0.00(2)	1,933	D
Stock Option (right to buy)	$16.11	11/17/2022		D			205,503	(1)	04/10/2029	Common Stock	205,503	$0.00(5)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		68,501		(4)	(4)	Common Stock	68,501	$0.00(5)	68,501	D
Stock Option (right to buy)	$16.1	11/17/2022		D			3,308	(6)	12/18/2029	Common Stock	3,308	$0.00(7)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		1,103		(8)	(8)	Common Stock	1,103	$0.00(7)	1,103	D
Stock Option (right to buy)	$16.1	11/17/2022		D			68,792	(6)	12/18/2029	Common Stock	68,792	$0.00(9)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		22,931		(8)	(8)	Common Stock	22,931	$0.00(9)	22,931	D
Stock Option (right to buy)	$31.83	11/17/2022		D			4,486	(10)	12/09/2030	Common Stock	4,486	$0.00(11)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		816		(12)	(12)	Common Stock	816	$0.00(11)	816	D
Stock Option (right to buy)	$31.83	11/17/2022		D			96,514	(10)	12/09/2030	Common Stock	96,514	$0.00(13)	0	D
Restricted Stock Unit (right to buy)	(3)	11/17/2022		A		17,548		(12)	(12)	Common Stock	17,548	$0.00(13)	17,548	D

Explanation of Responses:

1. This cancelled option vested 25% on January 1, 2020 and the remaining 75% vests in 36 substantially equal monthly installments thereafter.

2. On November 17, 2022, the issuer canceled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on April 11, 2019. In exchange for such stock option, the reporting person received restricted stock units in the amount of 1,933.

3. Each restricted stock unit represents a right to receive one share of the issuer's common stock at the time of vesting for no consideration.

4. The restricted stock units will vest 98% on December 1, 2022, and 2% on December 1, 2023.

5. On November 17, 2022, the issuer canceled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on April 11, 2019. In exchange for such stock option, the reporting person received restricted stock units in the amount of 68,501.

6. This cancelled option vested 25% on January 1, 2021 and the remaining 75% vests in 36 substantially equal monthly installments thereafter.

7. On November 17, 2022, the issuer canceled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on December 19, 2019. In exchange for such stock option, the reporting person received restricted stock units in the amount of 1,103.

8. 73% of these RSUs will vest on December 1, 2022, 25% will vest on December 1, 2023 and the remaining 2% will vest on December 1, 2024.

9. On November 17, 2022, the issuer cancelled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on December 19, 2019. In exchange for such stock option, the reporting person received restricted stock units in the amount of 22,931.

10. This cancelled option vested 25% on January 1, 2022 and the remaining 75% vests in 36 substantially equal monthly installments thereafter.

11. On November 17, 2022, the issuer cancelled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on December 10, 2020. In exchange for such stock option, the reporting person received restricted stock units in the amount of 816.

12. 48% of these RSUs will vest on December 1, 2022, 25% will vest on December 1, 2023, another 25% will vest on December 1, 2024 and the remaining 2% will vest on December 1, 2025.

13. On November 17, 2022, the issuer cancelled, pursuant to the issuer's offer to exchange eligible options for new restricted stock units program, a stock option granted to the reporting person on December 10, 2020. In exchange for such stock option, the reporting person received restricted stock units in the amount of 17,548.

Remarks:

	/s/ Margaret Siegel as Attorney-in-Fact	11/18/2022
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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